Phenotypes associated with this allele

• Allele Symbol: Dennd5b^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:6402021
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dennd5b^em1(IMPC)Tcp/Dennd5b^em1(IMPC)Tcp	C57BL/6N-Dennd5b^em1(IMPC)Tcp/Tcp	MGI:6696714

Genotype
MGI:6696714

hm1

• Allelic Composition: Dennd5b^em1(IMPC)Tcp/Dennd5b^em1(IMPC)Tcp
• Genetic Background: C57BL/6N-Dennd5b^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Dennd5b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - TCP

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - TCP

increased freezing behavior ( J:211773 )

♂

IMPC - TCP

increased grip strength ( J:211773 )

♂

IMPC - TCP

cardiovascular system

decreased heart rate ( J:211773 )

♂

IMPC - TCP

prolonged RR interval ( J:211773 )

♂

IMPC - TCP

prolonged PR interval ( J:211773 )

IMPC - TCP

prolonged QT interval ( J:211773 )

♂

IMPC - TCP

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - TCP

growth/size/body

increased lean body mass ( J:211773 )

♀

IMPC - TCP

hematopoietic system

decreased red blood cell distribution width ( J:211773 )

♂

IMPC - TCP

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

IMPC - TCP

abnormal spleen morphology ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - TCP

decreased circulating cholesterol level ( J:211773 )

IMPC - TCP

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - TCP

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - TCP

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - TCP

decreased circulating total protein level ( J:211773 )

IMPC - TCP

improved glucose tolerance ( J:211773 )

♂

IMPC - TCP

immune system

increased leukocyte cell number ( J:211773 )

♀

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

IMPC - TCP

abnormal spleen morphology ( J:211773 )

♂

IMPC - TCP

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

♂

IMPC - TCP

abnormal bone structure ( J:211773 )

♀

IMPC - TCP

decreased bone mineral content ( J:211773 )

♀

IMPC - TCP

decreased bone mineral density ( J:211773 )

♀

IMPC - TCP