Phenotypes associated with this allele
immune system
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• mild day 28 post immunization with sheep red blood cells
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• mild day 28 post immunization with sheep red blood cells
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hematopoietic system
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• mild day 28 post immunization with sheep red blood cells
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• mild day 28 post immunization with sheep red blood cells
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immune system
N |
• mice exhibit a restoration of normal IgG1 levels in B cells compared with Mir146tm1.1Tmmc Tg(Cr2-cre)3Cgn mice
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• following immunization with sheep red blood cells in mixed bone marrow chimeras
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hematopoietic system
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• following immunization with sheep red blood cells in mixed bone marrow chimeras
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir146tm1.1Lfl mutation
(1 available);
any
Mir146 mutation
(9 available)
Tg(Cr2-cre)3Cgn mutation
(2 available)
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immune system
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• minimal in young un-immunized mice on GL7+PNA+, which is further exacerbated with age
• at 6 months of age in un-immunized mice
• in young mice immunized with sheep red blood cells
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• in young mice immunized with sheep red blood cells
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• at 6 months of age in un-immunized mice
• in young mice immunized with sheep red blood cells
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• SRBC-specific in young mice immunized with sheep red blood cells (SRBC)
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• following immunization with 4-hydroxy-3-nitrophenyl linked to Keyhole Limpet Hemocyanin (KLH) (NP-KLH) in alum
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• at 6 months of age in un-immunized mice
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hematopoietic system
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• minimal in young un-immunized mice on GL7+PNA+, which is further exacerbated with age
• at 6 months of age in un-immunized mice
• in young mice immunized with sheep red blood cells
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• in young mice immunized with sheep red blood cells
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• at 6 months of age in un-immunized mice
• in young mice immunized with sheep red blood cells
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• SRBC-specific in young mice immunized with sheep red blood cells (SRBC)
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• following immunization with 4-hydroxy-3-nitrophenyl linked to Keyhole Limpet Hemocyanin (KLH) (NP-KLH) in alum
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir146tm1.1Lfl mutation
(1 available);
any
Mir146 mutation
(9 available)
Tg(CD2-icre)4Kio mutation
(4 available)
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immune system
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• following immunization with sheep red blood cells similar to in B cell conditional knock-outs
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• following immunization with sheep red blood cells
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hematopoietic system
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• following immunization with sheep red blood cells similar to in B cell conditional knock-outs
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• following immunization with sheep red blood cells
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir146tm1.1Lfl mutation
(1 available);
any
Mir146 mutation
(9 available)
Tg(Cd4-cre)1Cwi mutation
(10 available)
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immune system
N |
• following immunization with sheep red blood cells, mice exhibit a wild-type response in elevation of germinal center B cells and T follicular helper cells
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immune system
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• in young unimmunized mice with a further increase in mice immunized with sheep red blood cells
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• in young unimmunized mice with a further increase in mice immunized with sheep red blood cells
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• in mice immunized with sheep red blood cells
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hematopoietic system
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• in young unimmunized mice with a further increase in mice immunized with sheep red blood cells
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• in young unimmunized mice with a further increase in mice immunized with sheep red blood cells
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• in mice immunized with sheep red blood cells
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