All Phenotypes Tg(Tyro3*-Gfp)1Sapc MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Tyro3*-Gfp)1Sapc
transgene insertion 1, Sabine Cordes
MGI:6284564

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	anx/anx Tg(Tyro3*-Gfp)1Sapc/? Tyro3^m1/Tyro3^m1	involves: C3HeB/FeJLe * C57BL/6J	MGI:6287394

Allelic Composition	anx/anx Tg(Tyro3*-Gfp)1Sapc/? Tyro3^m1/Tyro3^m1
Genetic Background	involves: C3HeB/FeJLe * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
anx mutation (1 available); any anx mutation (1 available)
Tg(Tyro3*-Gfp)1Sapc mutation (0 available)
Tyro3^m1 mutation (4 available); any Tyro3 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:241666 )

abnormal head movements ( J:241666 )

mortality/aging

premature death ( J:241666 )

growth/size/body

cachexia ( J:241666 )

• unlike wildtype Tyro3, transgenic expression of this R7W point mutant transgene fails to resuce the anx homozygous phenotype, specifically cachexia, death by 21 days of age, and behavioral phenotypes such as head tossing and tremors

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