Tg(Tyro3*-Gfp)1Sapc
Transgene Detail

Summary

• Symbol: Tg(Tyro3*-Gfp)1Sapc
• Name: transgene insertion 1, Sabine Cordes
• MGI ID: MGI:6284564
• Synonyms: huT3, R7W-Tyro3-GFP
• Transgene: Tg(Tyro3*-Gfp)1Sapc Location: unknown
• Alliance: Tg(Tyro3*-Gfp)1Sapc page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A mouse Tyro3 cDNA sequence with a C19T point mutation, which results in an arginine to tryptophan substitution at the 7th amino acid to mimic the point mutation in Tyro3^m1, and a c-terminal GFP sequence was randomly inserted into the genome. (J:241666)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:241666 Kim DY, et al., The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation. Dis Model Mech. 2017 May 01;10(5):581-595
• All: 1 reference(s)