All Phenotypes Gdpd3<em1Tsr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gdpd3^em1Tsr
endonuclease-mediated mutation 1,Theodora S Ross
MGI:6280493

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gdpd3^em1Tsr/Gdpd3^em1Tsr	C57BL/6J-Gdpd3^em1Tsr	MGI:6719560
cx2	Gdpd3^em1Tsr/Gdpd3^em1Tsr Hip1^{tm5.1(HIP1)Tsr}/Hip1^{tm5.1(HIP1)Tsr}	involves: C57BL/6 * C57BL/6J	MGI:6719561

Allelic Composition	Gdpd3^em1Tsr/Gdpd3^em1Tsr
Genetic Background	C57BL/6J-Gdpd3^em1Tsr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdpd3^em1Tsr mutation (1 available); any Gdpd3 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

normal phenotype ( J:267987 )

N	• mice are viable, fertile and overtly normal with no detectable phenotype abnormalities up to 2 years of age • surprisingly, no major alterations are observed in phosphocholine- or homocysteine-related metabolites relative to wild-type controls

Allelic Composition	Gdpd3^em1Tsr/Gdpd3^em1Tsr Hip1^{tm5.1(HIP1)Tsr}/Hip1^{tm5.1(HIP1)Tsr}
Genetic Background	involves: C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdpd3^em1Tsr mutation (1 available); any Gdpd3 mutation (14 available)
Hip1^{tm5.1(HIP1)Tsr} mutation (1 available); any Hip1 mutation (67 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

lordokyphosis ( J:267987 )

• mice exhibit a significantly earlier onset of kypholordosis with a smaller angle of the thoracic curvature noted at 10 months of age, indicating an accelerated and more severe kypholordotic phenotype relative to single Hip1^{tm5.1(HIP1)Tsr} homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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