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Allele Symbol Allele Name Allele ID |
Tg(tetO/CMV-Dek,-luc)317Siwe transgene insertion 317, Susanne Wells MGI:6200913 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• increased incidence of gross esophageal squamous cell carcinoma with stromal invasion in mice treated with 4NQO, a chemical carcinogen, as compared to 4NQO dox-treated mice
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• survival of mice treated with 4NQO is less than 60% as compared to 4NQO dox-treated mice, which survive to at least 45 weeks
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• increased incidence of gross esophageal squamous cell carcinoma with stromal invasion in mice treated with 4NQO, a chemical carcinogen, as compared to 4NQO dox-treated mice
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• increased incidence of gross esophageal squamous cell carcinoma with stromal invasion in mice treated with 4NQO, a chemical carcinogen, as compared to 4NQO dox-treated mice
• incidence of oral squamous cell carcinoma is not increased
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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