About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pfdn1em1(IMPC)J
endonuclease-mediated mutation 1, Jackson
MGI:6195846
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pfdn1em1(IMPC)J/Pfdn1em1(IMPC)J C57BL/6NJ-Pfdn1em1(IMPC)J/Mmjax MGI:6493017
ht2
 		Pfdn1em1(IMPC)J/Pfdn1+ C57BL/6NJ-Pfdn1em1(IMPC)J/Mmjax MGI:6461523


Genotype
MGI:6493017
hm1
Allelic
Composition		 Pfdn1em1(IMPC)J/Pfdn1em1(IMPC)J
Genetic
Background		 C57BL/6NJ-Pfdn1em1(IMPC)J/Mmjax
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pfdn1em1(IMPC)J mutation (2 available); any Pfdn1 mutation (171 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
hemorrhage ( J:211773 )
IMPC - JAX

craniofacial
cleft palate ( J:211773 )
IMPC - JAX

digestive/alimentary system
cleft palate ( J:211773 )
IMPC - JAX

embryo

growth/size/body
cleft palate ( J:211773 )
IMPC - JAX
abnormal embryo size ( J:211773 )
IMPC - JAX

limbs/digits/tail

mortality/aging




Genotype
MGI:6461523
ht2
Allelic
Composition		 Pfdn1em1(IMPC)J/Pfdn1+
Genetic
Background		 C57BL/6NJ-Pfdn1em1(IMPC)J/Mmjax
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pfdn1em1(IMPC)J mutation (2 available); any Pfdn1 mutation (171 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
limb grasping ( J:211773 )
IMPC - JAX




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory