homeostasis/metabolism
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• increased intestinal inflammation and mucosal dysplasia in mice treated with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
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• increased incidence rate and tumor numbers following treatment with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
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digestive/alimentary system
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• in mice treated with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
|
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• in mice treated with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
|
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• in a DSS-induced model mice show severe bloody stools, significant weight loss, and shorter colon lengths
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growth/size/body
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• seen in a substantial fraction of mice
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respiratory system
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• seen in a substantial fraction of mice
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vision/eye
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• seen in a substantial fraction of mice
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immune system
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• in a DSS-induced model mice show severe bloody stools, significant weight loss, and shorter colon lengths
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• increased intestinal inflammation in mice treated with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
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endocrine/exocrine glands
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• in mice treated with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
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neoplasm
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• increased incidence rate and tumor numbers following treatment with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
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cellular
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• in mice treated with azoxymethane and 3 rounds of dextran sodium sulfate compared to similarly treated controls
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