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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Marchf8tm1.1Lkle
targeted mutation 1.1 Ludger Klein
MGI:5819100
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Marchf8tm1.1Lkle/Marchf8tm1.1Lkle involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5903295
cx2
 		Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf8tm1.1Lkle/Marchf8tm1.1Lkle 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N MGI:5903297


Genotype
MGI:5903295
hm1
Allelic
Composition		 Marchf8tm1.1Lkle/Marchf8tm1.1Lkle
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Marchf8tm1.1Lkle mutation (0 available); any Marchf8 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:236611 )
N
• normal CD4+ T cell compartment in the thymus




Genotype
MGI:5903297
cx2
Allelic
Composition		 Cd83tm1.1Lnjt/Cd83tm1.1Lnjt
Marchf8tm1.1Lkle/Marchf8tm1.1Lkle
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd83tm1.1Lnjt mutation (0 available); any Cd83 mutation (15 available)
Marchf8tm1.1Lkle mutation (0 available); any Marchf8 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:236611 )
N
• normal CD4+ T cell compartment in the thymus unlike in Cd83tm1.1Lnjt homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory