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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rai1tm2.2Luo
targeted mutation 2.2, Liqun Luo
MGI:5817606
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rai1tm2.2Luo/Rai1+
Tg(Nes-cre)1Kln/? 		either: (involves: 129S1/Sv * C57BL/6 * SJL) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL) MGI:5817608
cn2
 		Rai1tm2.2Luo/Rai1tm2.1Luo
Tg(Nes-cre)1Kln/? 		either: (involves: 129S1/Sv * C57BL/6 * SJL) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL) MGI:5817614


Genotype
MGI:5817608
cn1
Allelic
Composition		 Rai1tm2.2Luo/Rai1+
Tg(Nes-cre)1Kln/?
Genetic
Background		 either: (involves: 129S1/Sv * C57BL/6 * SJL) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1tm2.2Luo mutation (0 available); any Rai1 mutation (73 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired coordination ( J:237687 )
• males exhibit a decreased latency to fall in wire hang test




Genotype
MGI:5817614
cn2
Allelic
Composition		 Rai1tm2.2Luo/Rai1tm2.1Luo
Tg(Nes-cre)1Kln/?
Genetic
Background		 either: (involves: 129S1/Sv * C57BL/6 * SJL) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rai1tm2.1Luo mutation (1 available); any Rai1 mutation (73 available)
Rai1tm2.2Luo mutation (0 available); any Rai1 mutation (73 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
obese ( J:237687 )
• female mice become overweight beginning at 7 weeks of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory