All Phenotypes Lyn<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lyn^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5756074

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lyn^{tm1b(EUCOMM)Hmgu}/Lyn^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Lyn^{tm1b(EUCOMM)Hmgu}/H	MGI:6262834

Allelic Composition	Lyn^{tm1b(EUCOMM)Hmgu}/Lyn^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Lyn^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0704_6_B11

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyn^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Lyn mutation (64 available)

Data Sources

IMPC Data for Lyn

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal gait ( J:211773 )

IMPC - HAR

craniofacial

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

endocrine/exocrine glands

small thymus ( J:211773 )

IMPC - HAR

growth/size/body

enlarged spleen ( J:211773 )

IMPC - HAR

increased spleen weight ( J:211773 )

IMPC - HAR

hematopoietic system

small thymus ( J:211773 )

IMPC - HAR

enlarged spleen ( J:211773 )

IMPC - HAR

increased spleen weight ( J:211773 )

IMPC - HAR

increased eosinophil cell number ( J:211773 )

IMPC - HAR

decreased erythrocyte cell number ( J:211773 )

IMPC - HAR

decreased hematocrit ( J:211773 )

IMPC - HAR

decreased hemoglobin content ( J:211773 )

IMPC - HAR

increased red blood cell distribution width ( J:211773 )

IMPC - HAR

increased neutrophil cell number ( J:211773 )

IMPC - HAR

thrombocytopenia ( J:211773 )

IMPC - HAR

increased mean platelet volume ( J:211773 )

IMPC - HAR

increased monocyte cell number ( J:211773 )

IMPC - HAR

decreased leukocyte cell number ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

IMPC - HAR

immune system

small thymus ( J:211773 )

IMPC - HAR

enlarged spleen ( J:211773 )

IMPC - HAR

increased spleen weight ( J:211773 )

IMPC - HAR

increased eosinophil cell number ( J:211773 )

IMPC - HAR

increased neutrophil cell number ( J:211773 )

IMPC - HAR

increased monocyte cell number ( J:211773 )

IMPC - HAR

decreased leukocyte cell number ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

skeleton

abnormal maxilla morphology ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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