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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdk12em1(IMPC)Tcp
endonuclease-mediated mutation 1, The Centre for Phenogenomics
MGI:5754588
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdk12em1(IMPC)Tcp/Cdk12em1(IMPC)Tcp C57BL/6NCrl-Cdk12em1(IMPC)Tcp/Tcp MGI:6262090
ht2
 		Cdk12em1(IMPC)Tcp/Cdk12+ C57BL/6NCrl-Cdk12em1(IMPC)Tcp/Tcp MGI:6262089


Genotype
MGI:6262090
hm1
Allelic
Composition		 Cdk12em1(IMPC)Tcp/Cdk12em1(IMPC)Tcp
Genetic
Background		 C57BL/6NCrl-Cdk12em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk12em1(IMPC)Tcp mutation (2 available); any Cdk12 mutation (75 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6262089
ht2
Allelic
Composition		 Cdk12em1(IMPC)Tcp/Cdk12+
Genetic
Background		 C57BL/6NCrl-Cdk12em1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk12em1(IMPC)Tcp mutation (2 available); any Cdk12 mutation (75 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system

growth/size/body
increased heart weight ( J:211773 )
IMPC - TCP
enlarged urinary bladder ( J:211773 )
IMPC - TCP
enlarged spleen ( J:211773 )
IMPC - TCP
increased spleen weight ( J:211773 )
IMPC - TCP

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - TCP

homeostasis/metabolism

immune system
enlarged spleen ( J:211773 )
IMPC - TCP

liver/biliary system

renal/urinary system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory