Phenotypes associated with this allele

• Allele Symbol: Adnp2^em3(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 3, The Centre for Phenogenomics
• Allele ID: MGI:5754578
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adnp2^em3(IMPC)Tcp/Adnp2^em3(IMPC)Tcp	C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp	MGI:6261817
ht2	Adnp2^em3(IMPC)Tcp/Adnp2^+	C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp	MGI:6394239

Genotype
MGI:6261817

hm1

• Allelic Composition: Adnp2^em3(IMPC)Tcp/Adnp2^em3(IMPC)Tcp
• Genetic Background: C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Adnp2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

♂

IMPC - TCP

growth/size/body

decreased body length ( J:211773 )

IMPC - TCP

homeostasis/metabolism

decreased circulating total protein level ( J:211773 )

♀

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

IMPC - TCP

liver/biliary system

abnormal liver morphology ( J:211773 )

♀

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - TCP

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - TCP

respiratory system

abnormal lung morphology ( J:211773 )

♀

IMPC - TCP

skeleton

short tibia ( J:211773 )

IMPC - TCP

abnormal bone structure ( J:211773 )

♀

IMPC - TCP

decreased bone mineral content ( J:211773 )

♀

IMPC - TCP

decreased bone mineral density ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:6394239

ht2

• Allelic Composition: Adnp2^em3(IMPC)Tcp/Adnp2⁺
• Genetic Background: C57BL/6NCrl-Adnp2^em3(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Adnp2

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - TCP

endocrine/exocrine glands

absent adrenal gland ( J:211773 )

♀

IMPC - TCP

small adrenal glands ( J:211773 )

♂

IMPC - TCP

abnormal thymus morphology ( J:211773 )

♀

IMPC - TCP

abnormal ovary morphology ( J:211773 )

♀

IMPC - TCP

hematopoietic system

abnormal thymus morphology ( J:211773 )

♀

IMPC - TCP

small spleen ( J:211773 )

♀

IMPC - TCP

immune system

abnormal thymus morphology ( J:211773 )

♀

IMPC - TCP

small spleen ( J:211773 )

♀

IMPC - TCP

enlarged lymph nodes ( J:211773 )

♀

IMPC - TCP

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - TCP

renal/urinary system

small kidney ( J:211773 )

♀

IMPC - TCP

reproductive system

abnormal ovary morphology ( J:211773 )

♀

IMPC - TCP

small uterus ( J:211773 )

♀

IMPC - TCP

skeleton

abnormal sternum morphology ( J:211773 )

♀

IMPC - TCP

vision/eye

cataract ( J:211773 )

IMPC - TCP