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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ranbp9tm1.1Wyan
targeted mutation 1.1, Wei Yan
MGI:5702969
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ranbp9tm1.1Wyan/Ranbp9tm1.1Wyan Not Specified MGI:5703004


Genotype
MGI:5703004
hm1
Allelic
Composition
Ranbp9tm1.1Wyan/Ranbp9tm1.1Wyan
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ranbp9tm1.1Wyan mutation (0 available); any Ranbp9 mutation (40 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• only about 6% of mice survive to adulthood
• neonatal lethality, with about 6% of mice surviving to adulthood

growth/size/body

reproductive system
• reduction in total number of spermatogenic cells, however spermatogenesis proceeds through meiosis and reaches round spermatid and even elongated spermatid stages
• spermatocytes and spermatids appear to be constantly depleted, leading to a complete lack of spermatozoa in the epididymis
• about 2-fold increase in apoptotic cells, mainly spermatocytes and early round spermatids, in the testes
• males are completely infertile

cellular
• reduction in total number of spermatogenic cells, however spermatogenesis proceeds through meiosis and reaches round spermatid and even elongated spermatid stages
• spermatocytes and spermatids appear to be constantly depleted, leading to a complete lack of spermatozoa in the epididymis
• about 2-fold increase in apoptotic cells, mainly spermatocytes and early round spermatids, in the testes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory