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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		NipblGt(EUCE313f02)1.1Hmgu
gene trap EUCE313f02, 1.1, Helmholtz Zentrum Muenchen GmbH
MGI:5644433
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Foxa2tm1(cre)Heli/Foxa2+ 		involves: 129P2/OlaHsd * 129S2/SvPas * CD-1 MGI:7492232
cn2
 		NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Sox17tm2.1(icre)Heli/Sox17+ 		involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1 MGI:7492228
cn3
 		NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Tg(Nanog-cre)#Vlcg/0 		involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NTac * CD-1 MGI:7492239
cn4
 		NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Tg(Tnnt2-cre)5Blh/0 		involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2 MGI:7492222
cn5
 		H2az2Tg(Wnt1-cre)11Rth/H2az2+
NipblGt(EUCE313f02)1.1Hmgu/Nipbl+ 		involves: 129P2/OlaHsd * C57BL/6J * CBA/J * CD-1 MGI:7492235


Genotype
MGI:7492232
cn1
Allelic
Composition		 NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Foxa2tm1(cre)Heli/Foxa2+
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxa2tm1(cre)Heli mutation (0 available); any Foxa2 mutation (30 available)
NipblGt(EUCE313f02)1.1Hmgu mutation (0 available); any Nipbl mutation (125 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
atrial septal defect ( J:236978 )
• in 26% of hearts at E17.5




Genotype
MGI:7492228
cn2
Allelic
Composition		 NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Sox17tm2.1(icre)Heli/Sox17+
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.1Hmgu mutation (0 available); any Nipbl mutation (125 available)
Sox17tm2.1(icre)Heli mutation (0 available); any Sox17 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:236978 )
• heart size is similar to wild-type
atrial septal defect ( J:236978 )
• in 26% of hearts at E17.5

growth/size/body
growth/size/body region phenotype ( J:236978 )
• body size is similar to wild-type




Genotype
MGI:7492239
cn3
Allelic
Composition		 NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Tg(Nanog-cre)#Vlcg/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NTac * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.1Hmgu mutation (0 available); any Nipbl mutation (125 available)
Tg(Nanog-cre)#Vlcg mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
atrial septal defect ( J:236978 )
• large defects in 33% of hearts at E17.5




Genotype
MGI:7492222
cn4
Allelic
Composition		 NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Tg(Tnnt2-cre)5Blh/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CD-1 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.1Hmgu mutation (0 available); any Nipbl mutation (125 available)
Tg(Tnnt2-cre)5Blh mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:236978 )
N
• heart size is similar to wild-type
atrial septal defect ( J:236978 )
• in 30% of hearts at E17.5

growth/size/body
growth/size/body region phenotype ( J:236978 )
N
• body size is similar to wild-type




Genotype
MGI:7492235
cn5
Allelic
Composition		 H2az2Tg(Wnt1-cre)11Rth/H2az2+
NipblGt(EUCE313f02)1.1Hmgu/Nipbl+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J * CBA/J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
NipblGt(EUCE313f02)1.1Hmgu mutation (0 available); any Nipbl mutation (125 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:236978 )
N
• no heart defects are seen




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory