Phenotypes associated with this allele

• Allele Symbol: Cep19^tm1.1Jmgi
• Allele Name: targeted mutation 1.1, John Martignetti
• Allele ID: MGI:5576737
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep19^tm1.1Jmgi/Cep19^tm1.1Jmgi	involves: 129S2/SvPas * C57BL/6J	MGI:5576749

Genotype
MGI:5576749

hm1

• Allelic Composition: Cep19^tm1.1Jmgi/Cep19^tm1.1Jmgi
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:206667 )

• at 8 and 13 weeks, respectively, in male and female mice

obese ( J:206667 )

increased body length ( J:206667 )

homeostasis/metabolism

decreased oxygen consumption ( J:206667 )

• however, oxygen consumption normalized to lean body mass is normal

increased respiratory quotient ( J:206667 )

behavior/neurological

polyphagia ( J:206667 )

• hyperphagic mice with increased food consumption compared with wild-type mice

• however, food consumption normalized to lean body mass is normal

decreased locomotor activity ( J:206667 )

adipose tissue

increased total body fat amount ( J:206667 )

• 2-fold increase

increased percent body fat/body weight ( J:206667 )

• 2-fold increase