Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{tm1.1(Ubc-BCL3)Sbn}
• Allele Name: targeted mutation 1.1, Ulrich Siebenlist
• Allele ID: MGI:5574305
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm1.1(Ubc-BCL3)Sbn/Gt(ROSA)26Sor^+ Cd79a^tm1(cre)Reth/Cd79a^+	involves: BALB/c * C57BL/6	MGI:5574306

Genotype
MGI:5574306

cn1

• Allelic Composition: Gt(ROSA)26Sor^{tm1.1(Ubc-BCL3)Sbn}/Gt(ROSA)26Sor⁺; Cd79a^tm1(cre)Reth/Cd79a⁺
• Genetic Background: involves: BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased B cell proliferation ( J:207111 )

• slightly less in LPS-stimulated marginal zone

• however, proliferation of alphaIgM-stimulated follicular B cells is not significantly different from that of wild-type cells

decreased follicular B cell number ( J:207111 )

• FO I B cells

decreased marginal zone B cell number ( J:207111 )

increased follicular B cell number ( J:207111 )

• total and FO II B cells

hematopoietic system

decreased B cell proliferation ( J:207111 )

• slightly less in LPS-stimulated marginal zone

• however, proliferation of alphaIgM-stimulated follicular B cells is not significantly different from that of wild-type cells

decreased follicular B cell number ( J:207111 )

• FO I B cells

decreased marginal zone B cell number ( J:207111 )

increased follicular B cell number ( J:207111 )

• total and FO II B cells

cellular

decreased B cell proliferation ( J:207111 )

• slightly less in LPS-stimulated marginal zone

• however, proliferation of alphaIgM-stimulated follicular B cells is not significantly different from that of wild-type cells