Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(tTA,CMV*1-KIAA1549/BRAF,-EGFP)Gtm mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
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nervous system
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• increased neuronal stem cell proliferation following transfection with a cre-expressing adenovirus
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• following transfection with a cre-expressing adenovirus
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(tTA,CMV*1-KIAA1549/BRAF,-EGFP)Gtm mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Tg(Fabp7-cre,-lacZ)3Gtm mutation
(1 available)
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mortality/aging
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• mice are born in Mendelian ratios but do not survive beyond 8 to 10 weeks
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digestive/alimentary system
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• abnormal alimentary canal, ranging from severely swollen stomachs to blackened hindguts
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• blackened hindguts in some mice
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• severely swollen in some mice
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• mice become malnourished
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nervous system
N |
• cell proliferation and survival are normal in the cerebellum
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• GFAP+ and S100B+ without a change in proliferation or apoptosis rates
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(tTA,CMV*1-KIAA1549/BRAF,-EGFP)Gtm mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Tg(GFAP-cre)#Gtm mutation
(0 available)
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nervous system
N |
• mice exhibit normal GFAP+ and S100B+ astrocytes cell numbers
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(tTA,CMV*1-KIAA1549/BRAF,-EGFP)Gtm mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Ifi208Tg(Cspg4-cre)1Akik mutation
(1 available);
any
Ifi208 mutation
(36 available)
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nervous system
N |
• mice exhibit normal GFAP+ and S100B+ astrocytes cell numbers
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