All Phenotypes Nr6a1<tm1d(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nr6a1^{tm1d(EUCOMM)Wtsi}
targeted mutation 1d, Wellcome Trust Sanger Institute
MGI:5532717

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nr6a1^{tm1d(EUCOMM)Wtsi}/Nr6a1^{tm1d(EUCOMM)Wtsi}	involves: 129S/SvEv * C57BL/6 * C57BL/6N * SJL	MGI:5532735

Allelic Composition	Nr6a1^{tm1d(EUCOMM)Wtsi}/Nr6a1^{tm1d(EUCOMM)Wtsi}
Genetic Background	involves: 129S/SvEv * C57BL/6 * C57BL/6N * SJL
Cell Lines	EPD0105_6_D03

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr6a1^{tm1d(EUCOMM)Wtsi} mutation (0 available); any Nr6a1 mutation (145 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Morphological defects in E9.5 Nr6a1^{tm1d(EUCOMM)Wtsi}/Nr6a1^{tm1d(EUCOMM)Wtsi} embryos

mortality/aging

embryonic lethality, complete penetrance ( J:204241 )

• authors state that mice exhibit severe morphological defects similar to those in Nr6a1^tm1Coo homozygotes

embryo

abnormal embryo development ( J:204241 )

• authors state that mice exhibit severe morphological defects similar to those in Nr6a1^tm1Coo homozygotes

incomplete embryo turning ( J:204241 )

• embryos fail to turn from the lordotic to the fetal position

decreased embryo size ( J:204241 )

• at E9.5

impaired somite development ( J:204241 )

• truncated somitogenesis

growth/size/body

decreased embryo size ( J:204241 )

• at E9.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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