Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nr6a1tm1Coo
Name:	nuclear receptor subfamily 6, group A, member 1; targeted mutation 1, Austin J Cooney
MGI ID:	MGI:2385846
Synonyms:	GCNF-
Gene:	Nr6a1  Location: Chr2:38613381-38816473 bp, - strand  Genetic Position: Chr2, 24.42 cM
Alliance:	Nr6a1tm1Coo page

Germline Transmission:	Earliest citation of germline transmission: J:67377
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The exon encoding the DNA-binding domain was replaced with a neomycin selection cassette. Transcript was undetected via in situ hybridization of homozygous mutant embryos. (J:67377)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	39 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr6a1 Mutation:	145 strains or lines available

Original:	J:67377 Chung AC, et al., Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan;21(2):663-77
All:	7 reference(s)