Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2rtm1.1(IGF2R)Arte mutation
(0 available);
any
Igf2r mutation
(98 available)
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mortality/aging
N |
• rescue of preweaning lethality observed when Igf2rtm1.1(IGF2R)Arte is inherited maternally
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growth/size/body
N |
• rescue of postnatal overgrowth observed when Igf2rtm1.1(IGF2R)Arte is inherited maternally
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2rtm1.1(IGF2R)Arte mutation
(0 available);
any
Igf2r mutation
(98 available)
|
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Increased body size in Igf2rtm1.1(IGF2R)Arte/Igf2r+ mice when the allele is inherited maternally
mortality/aging
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• when the allele is inherited maternally, fewer than expected pups survive to P10
• however, all pups are viable when this allele is inherited paternally
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reproductive system
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• dilated, enlarged and fluid filled when the allele is inherited maternally
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• when the allele is inherited maternally
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• when the allele is inherited maternally
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• when the allele is inherited maternally
• however, all pups are viable when this allele is inherited paternally
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cardiovascular system
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• at E14.5 and at E18.5 without hypertrophy when the allele is inherited maternally
• however, heart weight was not disproportional at E18.5
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• increased ventricular muscle with blood filled spaces at E18.5 when the allele is inherited maternally
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• when the allele is inherited maternally
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• increased ventricular muscle with blood filled spaces at E18.5 when the allele is inherited maternally
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growth/size/body
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• at E14.5 and at E18.5 without hypertrophy when the allele is inherited maternally
• however, heart weight was not disproportional at E18.5
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• when the allele is inherited maternally
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• when the allele is inherited maternally
• however, adult weight is normal when the allele is inherited paternally
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• at E14.5, E17.5 and E18.5 when the allele is inherited maternally
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embryo
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• at E14.5 and E18.5 when the allele is inherited maternally
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2rtm1.1(IGF2R)Arte mutation
(0 available);
any
Igf2r mutation
(98 available)
Igf2rtm2Wag mutation
(1 available);
any
Igf2r mutation
(98 available)
|
|
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mortality/aging
N |
• rescue of preweaning lethality observed when Igf2rtm1.1(IGF2R)Arte is inherited maternally
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2rtm1.1(IGF2R)Arte mutation
(0 available);
any
Igf2r mutation
(98 available)
Igf2tm1Rob mutation
(1 available);
any
Igf2 mutation
(25 available)
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|
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mortality/aging
N |
• rescue of preweaning lethality observed when Igf2rtm1.1(IGF2R)Arte is inherited maternally
|
growth/size/body
N |
• rescue of postnatal overgrowth observed when Igf2rtm1.1(IGF2R)Arte is inherited maternally
|