Phenotypes associated with this allele
neoplasm
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• in a model of non-small cell lung carcinoma, mice exposed to a cre-expressing adenovirus exhibit fewer tumors and smaller tumor area compared with Krastm4Tyj/Kras+ Ralatm1.2Cjm/Rala+ Ralbtm1.1Cjm/Ralbtm1.2Cjm control mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralatm1.2Cjm mutation
(2 available);
any
Rala mutation
(26 available)
Ralbtm1.1Cjm mutation
(0 available);
any
Ralb mutation
(47 available)
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cellular
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• in mouse embryonic fibroblasts infected with a cre-expressing adenovirus
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cellular
N |
• mouse embryonic fibroblasts infected with a cre-expressing adenovirus exhibit normal proliferation
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralatm1.2Cjm mutation
(2 available);
any
Rala mutation
(26 available)
Tg(Fabp4-cre)1Rev mutation
(2 available)
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mortality/aging
N |
• mice exhibit normal viability
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralatm1.2Cjm mutation
(2 available);
any
Rala mutation
(26 available)
Tg(KRT14-cre)8Brn mutation
(4 available)
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neoplasm
N |
• DMBA-TPA-treated mice exhibit normal tumor formation
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