Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eef1a1tm2Arge mutation
(0 available);
any
Eef1a1 mutation
(60 available)
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation
(2 available);
any
Gt(ROSA)26Sor mutation
(944 available)
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hematopoietic system
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• leukemia-initiating cells plated in methylcellulose cultures in the presence of tamoxifen exhibit decreased blast colony number and loss of blast colony formation due to increased apoptosis compared with control cells
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eef1a1tm2Arge mutation
(0 available);
any
Eef1a1 mutation
(60 available)
Tg(Mx1-cre)1Cgn mutation
(7 available)
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neoplasm
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• T cell acute lymphoblastic leukemia (T-ALL)
• progressive leukemic cells infiltrate the leptomeningeal spaces of the brain
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immune system
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• atypical CD4+CD8+ T cells in the peripheral blood
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hematopoietic system
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• atypical CD4+CD8+ T cells in the peripheral blood
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