Analysis Tools
hematopoietic system
| N |
• mice exhibit normal lymphoid differentiation in the bone marrow, spleen and thymus and normal numbers of hematopoietic stem cells
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Allele Symbol Allele Name Allele ID |
Gfi1tm6.1(GFI1)Tmo targeted mutation 6.1, Tarik Moroy MGI:5468264 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal lymphoid differentiation in the bone marrow, spleen and thymus and normal numbers of hematopoietic stem cells
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• of all pIpC-treated mice
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• all pIpC-treated mice die of myeloproliferative disorder accompanied by an expansion of myeloid cells in the bone marrow, an infiltration of myeloid cells in the spleen, and the appearance of blast cells in the blood faster
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• all pIpC-treated mice die of myeloproliferative disorder accompanied by an expansion of myeloid cells in the bone marrow, an infiltration of myeloid cells in the spleen, and the appearance of blast cells in the blood faster
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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