Analysis Tools
immune system
| N |
• mice exhibit normal B cell development in the bone marrow and spleen
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• following with activation LPS, less so when activated with LPS plus IL4
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• following activated with LPS and IL4, mice exhibit decreased IgG1+ cells, indicating reduced class switch recombination, compared with wild-type mice
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• following immunization with NP-CGG in alum, splenic B cells exhibit reduced mutation frequency in the rearranged Vh186.2 H chains compared with wild-type cells
• Peyer's patch B cells exhibit reduced accumulation of mutation at the intron downstream of rearranged V genes compared with wild-type cells
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hematopoietic system
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• following with activation LPS, less so when activated with LPS plus IL4
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• following activated with LPS and IL4, mice exhibit decreased IgG1+ cells, indicating reduced class switch recombination, compared with wild-type mice
|
|
• following immunization with NP-CGG in alum, splenic B cells exhibit reduced mutation frequency in the rearranged Vh186.2 H chains compared with wild-type cells
• Peyer's patch B cells exhibit reduced accumulation of mutation at the intron downstream of rearranged V genes compared with wild-type cells
|
cellular
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• following with activation LPS, less so when activated with LPS plus IL4
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