All Phenotypes Crim1<tm1.1Dpen> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Crim1^tm1.1Dpen
targeted mutation 1.1, David J Pennisi
MGI:5438615

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crim1^tm1.1Dpen/Crim1^tm1.1Dpen	B6.129P2(129S7)-Crim1^tm1.1Dpen	MGI:5438633
hm2	Crim1^tm1.1Dpen/Crim1^tm1.1Dpen	either: (B6.129P2(129S7)-Crim1^tm1.1Dpen) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)	MGI:5438635
hm3	Crim1^tm1.1Dpen/Crim1^tm1.1Dpen	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1	MGI:5438634

Allelic Composition	Crim1^tm1.1Dpen/Crim1^tm1.1Dpen
Genetic Background	B6.129P2(129S7)-Crim1^tm1.1Dpen

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crim1^tm1.1Dpen mutation (0 available); any Crim1 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

Allelic Composition	Crim1^tm1.1Dpen/Crim1^tm1.1Dpen
Genetic Background	either: (B6.129P2(129S7)-Crim1^tm1.1Dpen) or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crim1^tm1.1Dpen mutation (0 available); any Crim1 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

renal hypoplasia ( J:187855 )

homeostasis/metabolism

edema ( J:187855 )

• in some mice, noted as early as E14.5

integument

bleb ( J:187855 )

• peridermal blebbing at E12.5 and E13.5

limbs/digits/tail

syndactyly ( J:187855 )

• mild at E13.5

vision/eye

microphthalmia ( J:187855 )

• eye hypoplasia from E13.5

Allelic Composition	Crim1^tm1.1Dpen/Crim1^tm1.1Dpen
Genetic Background	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crim1^tm1.1Dpen mutation (0 available); any Crim1 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality, incomplete penetrance ( J:187855 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24