Analysis Tools
digestive/alimentary system
| N |
• mice exhibit normal cholesterol absorption
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Allele Symbol Allele Name Allele ID |
Soat2tm1.1Llr targeted mutation 1.1, Lawrence L Rudel MGI:5426949 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal cholesterol absorption
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• in mice fed a 0.05% cholesterol diet
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• in mice fed a 0.05% cholesterol diet
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• in mice fed a 0.1% or 0.5% dietary cholesterol
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• regardless of dietary cholesterol percentage
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• total cholesterol and cholesteryl ester regardless of dietary cholesterol percentage
• free cholesterol when fed a 0.5% cholesterol diet
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• when fed a 0.5% cholesterol diet
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• total cholesterol and cholesteryl ester regardless of dietary cholesterol percentage
• free cholesterol when fed a 0.5% cholesterol diet
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• when fed a 0.5% cholesterol diet
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| N |
• mice exhibit normal cholesterol absorption
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• regardless of dietary cholesterol percentage, mice exhibit decreased cholesterol absorption compared with control mice
• when fed 0.05% or 0.1% dietary cholesterol, mice exhibit increased fecal cholesterol loss compared with control mice
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• in mice fed a 0.05% or 0.5% dietary cholesterol
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• decreased biliary cholesterol regardless of dietary cholesterol percentage
• decreased cholesteryl ester in intestinal enterocytes regardless of dietary cholesterol percentage
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• in mice fed a 0.05% or 0.5% dietary cholesterol
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• in mice fed a 0.1% or 0.5% dietary cholesterol
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• total cholesterol and cholesteryl ester regardless of dietary cholesterol percentage
• free cholesterol when fed a 0.5% cholesterol diet
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• total and free cholesterol are increased in intestinal enterocytes of mice fed a 0.5% cholesterol diet
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• when fed a 0.5% cholesterol diet
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• regardless of dietary cholesterol percentage, mice exhibit decreased cholesterol absorption compared with control mice
• when fed 0.05% or 0.1% dietary cholesterol, mice exhibit increased fecal cholesterol loss compared with control mice
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• total cholesterol and cholesteryl ester regardless of dietary cholesterol percentage
• free cholesterol when fed a 0.5% cholesterol diet
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• when fed a 0.5% cholesterol diet
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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