Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbxa2rtm1.1Bhk mutation
(1 available);
any
Tbxa2r mutation
(17 available)
Tbxa2rtm1Cof mutation
(0 available);
any
Tbxa2r mutation
(17 available)
Tg(Nes-cre)1Kln mutation
(4 available)
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respiratory system
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• mice exposed to ovalbumin and U-46619 fail to exhibit increased airway resistance unlike control mice
• however, mice exposed to increasing doses of thromboxane receptor agonist U-46619 exhibit dose-dependent increase in airway resistance
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbxa2rtm1.1Bhk mutation
(1 available);
any
Tbxa2r mutation
(17 available)
Tbxa2rtm1Cof mutation
(0 available);
any
Tbxa2r mutation
(17 available)
Tg(Tagln-cre)1Her mutation
(2 available)
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respiratory system
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• mice exposed to increasing doses of thromboxane receptor agonist U-46619 exhibit an attenuated dose-dependent increase in airway resistance unlike control mice
• mice exposed to U-46619 and methacholine exhibit less of an increased in airway resistance compared with control mice
• however, mice exposed ovalbumin and U-46619 exhibit dose-dependent increase in airway resistance
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