Tbxa2r^tm1.1Bhk
Targeted Allele Detail

Summary

• Symbol: Tbxa2r^tm1.1Bhk
• Name: thromboxane A2 receptor; targeted mutation 1.1, Beverly H Koller
• MGI ID: MGI:5319073
• Synonyms: Tbxa2r^F
• Gene: Tbxa2r Location: Chr10:81164565-81171006 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Tbxa2r^tm1.1Bhk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183333
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 2 floxed. (J:183333)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbxa2r Mutation: 17 strains or lines available

References

• Original: J:183333 Cyphert JM, et al., Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse. Am J Physiol Lung Cell Mol Physiol. 2012 Jan;302(1):L140-51
• All: 3 reference(s)