All Phenotypes Col1a1<tm11(tetO-Dnmt3b

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Col1a1^{tm11(tetO-Dnmt3b_i6)Jae}
targeted mutation 11, Rudolf Jaenisch
MGI:5313407

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Apc^Min/Apc⁺ Col1a1^{tm11(tetO-Dnmt3b_i6)Jae}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTA*M2)Jae}/Gt(ROSA)26Sor⁺	involves: 129S4/SvJae * C57BL/6 * C57BL/6J	MGI:5313421

Allelic Composition	Apc^Min/Apc⁺ Col1a1^{tm11(tetO-Dnmt3b_i6)Jae}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTA*M2)Jae}/Gt(ROSA)26Sor⁺
Genetic Background	involves: 129S4/SvJae * C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^Min mutation (12 available); any Apc mutation (154 available)
Col1a1^{tm11(tetO-Dnmt3b_i6)Jae} mutation (0 available); any Col1a1 mutation (160 available)
Gt(ROSA)26Sor^{tm1(rtTA*M2)Jae} mutation (30 available); any Gt(ROSA)26Sor mutation (944 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

neoplasm ( J:127808 )

N	• doxycycline-treated mice develop intestinal adenomas at the same rate as in Apc^min heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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