Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm3Kba mutation
(0 available);
any
Ctnnb1 mutation
(49 available)
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mortality/aging
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• total failure of embryonic development at E7.5
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embryo
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• strong defects in gastrulation are visible at E7.5
• total failure of embryonic development at E7.5
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nervous system
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• differentiation of sensory neurons in the neural tube is defective
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• milder defects than in conditional mutant mice homozygous for Ctnnb1tm2Kem at E12.5
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craniofacial
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• milder defects than in conditional mutant mice homozygous for Ctnnb1tm2Kem at E12.5
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embryo
N |
• apical neural tube morphology is not disrupted at E12.5
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cellular
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• differentiation of sensory neurons in the neural tube is defective
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nervous system
craniofacial
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• hypoplastic and malformed
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skeleton
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• hypoplastic and malformed
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