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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Capn2tm2.1Tcs
targeted mutation 2.1, Takaomi C Saido
MGI:5292735
Summary 3 genotypes


Genotype
MGI:5292736
cn1
Allelic
Composition		 Capn2tm1Tcs/Capn2tm2.1Tcs
Meox2tm1(cre)Sor/Meox2+
Genetic
Background		 B6.129S-Capn2tm1Tcs/Capn2tm2.1Tcs Meox2tm1(cre)Sor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn2tm1Tcs mutation (1 available); any Capn2 mutation (35 available)
Capn2tm2.1Tcs mutation (1 available); any Capn2 mutation (35 available)
Meox2tm1(cre)Sor mutation (3 available); any Meox2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal survival ( J:175868 )
• about half survive to adulthood




Genotype
MGI:5292738
cn2
Allelic
Composition		 Capn1tm1Ahc/Capn1tm1Ahc
Capn2tm1Tcs/Capn2tm2.1Tcs
Meox2tm1(cre)Sor/Meox2+
Genetic
Background		 B6.129-Capn2tm1Tcs/Capn2tm2.1Tcs Meox2tm1(cre)Sor Capn1tm1Ahc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn1tm1Ahc mutation (1 available); any Capn1 mutation (33 available)
Capn2tm1Tcs mutation (1 available); any Capn2 mutation (35 available)
Capn2tm2.1Tcs mutation (1 available); any Capn2 mutation (35 available)
Meox2tm1(cre)Sor mutation (3 available); any Meox2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal survival ( J:175868 )
• about half survive to adulthood




Genotype
MGI:5292743
cn3
Allelic
Composition		 Capn1tm1Ahc/Capn1tm1Ahc
Capn2tm2.1Tcs/Capn2tm2.1Tcs
Tg(Tek-cre)12Flv/0
Genetic
Background		 B6.Cg-Capn2tm2.1Tcs Capn1tm1Ahc Tg(Tek-cre)12Flv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Capn1tm1Ahc mutation (1 available); any Capn1 mutation (33 available)
Capn2tm2.1Tcs mutation (1 available); any Capn2 mutation (35 available)
Tg(Tek-cre)12Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:175868 )
• viable with no significant abnormalities detected for at least 1 year




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory