Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a37tm1.2Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
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mortality/aging
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• pale embryos found at E9.5
• no homozygous embryos at E11.5
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integument
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• E9.5 embryos are noticeably paler than control embryos
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hematopoietic system
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• no hemoglobinization in the yolk sac and heart
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a37tm1.1Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
Slc25a37tm1.2Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
Tg(Mx1-cre)1Cgn mutation
(7 available)
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hematopoietic system
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• increased in the spleen in mice treated with poly (I:C)
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• ineffective erythropoiesis in bone marrow and spleen in mice treated with poly (I:C)
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• development of anemia in mice treated with poly (I:C)
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• 5 fold increase in splenic erythroid progenitor cells in mice treated with poly (I:C)
• 10 fold increase in primitive erythroid progenitor cells in bone marrow
• increased number of non-viable cells in both spleen and bone marrow
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• 2 fold increase in bone marrow in mice treated with poly (I:C)
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• decreased red blood cell number in mice treated with poly (I:C)
• 50% decrease in mature red blood cell numbers in bone marrow
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• in mice treated with poly (I:C)
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• in mice treated with poly (I:C)
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• in mice treated with poly (I:C)
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• 6 fold decrease in cell number in mice treated with poly (I:C)
• four fold decrease in B cell lineage cells in bone marrow
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• 4 fold decrease in cell number mice treated with poly (I:C)
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• changes in spleen architecture in mice treated with poly (I:C)
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• in mice treated with poly (I:C)
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immune system
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• 6 fold decrease in cell number in mice treated with poly (I:C)
• four fold decrease in B cell lineage cells in bone marrow
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• 4 fold decrease in cell number mice treated with poly (I:C)
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• changes in spleen architecture in mice treated with poly (I:C)
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• in mice treated with poly (I:C)
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growth/size/body
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• in mice treated with poly (I:C)
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a37tm1.1Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
Slc25a37tm1.2Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation
(6 available);
any
Speer6-ps1 mutation
(4 available)
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mortality/aging
homeostasis/metabolism
liver/biliary system
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• when fed delta aminolevulinic acid
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• increased collagen deposition when fed delta aminolevulinic acid, also occurs to a to lesser extent in heterozygotes
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• bile accumulation occurs when fed delta aminolevulinic acid
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hematopoietic system
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• slightly enlarged when fed delta aminolevulinic acid
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immune system
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• slightly enlarged when fed delta aminolevulinic acid
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growth/size/body
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• when fed delta aminolevulinic acid
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• slightly enlarged when fed delta aminolevulinic acid
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a37tm1.1Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
Slc25a37tm1.2Kapl mutation
(0 available);
any
Slc25a37 mutation
(9 available)
Tg(Tek-cre)1Ywa mutation
(6 available)
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mortality/aging
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• no live mice can be identified
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