Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(Rnf187)Jhai mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Krastm4Tyj mutation
(9 available);
any
Kras mutation
(76 available)
Tg(Vil1-cre)20Syr mutation
(3 available)
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digestive/alimentary system
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• mice exhibit increased cell proliferation in the colonic crypt compared with wild-type mice
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cellular
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• mice exhibit increased cell proliferation in the colonic crypt compared with wild-type mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation
(12 available);
any
Apc mutation
(154 available)
Gt(ROSA)26Sortm2(Rnf187)Jhai mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(942 available)
Tg(Vil1-cre)20Syr mutation
(3 available)
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neoplasm
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• intestinal tumors are increased in number compared to in ApcMin/Apc+ Tg(Vil-cre)20Syr
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• intestinal tumors exhibit increased cell proliferation and size compared to in ApcMin/Apc+ Tg(Vil-cre)20Syr
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digestive/alimentary system
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• intestinal tumors are increased in number compared to in ApcMin/Apc+ Tg(Vil-cre)20Syr
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