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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Il10tm1Keny
targeted mutation 1, Kenya Honda
MGI:5005059
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Il10tm1Keny/Il10+
Nfil3tm1.1Kubo/Nfil3tm1.1Kubo 		involves: 129 * C57BL/6 MGI:5006686


Genotype
MGI:5006686
cx1
Allelic
Composition		 Il10tm1Keny/Il10+
Nfil3tm1.1Kubo/Nfil3tm1.1Kubo
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il10tm1Keny mutation (0 available); any Il10 mutation (44 available)
Nfil3tm1.1Kubo mutation (0 available); any Nfil3 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interleukin-10 secretion ( J:172134 )
• following MOG-treatment, fewer Il10+ T cells are detected in the spleen, intestinal intraepithelial lymphocytes, lamina propria, and bone marrow compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory