Phenotypes associated with this allele

• Allele Symbol: Jag2^tm2.2Grid
• Allele Name: targeted mutation 2.2, Tom Gridley
• Allele ID: MGI:4829505
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Jag2^tm2.2Grid/Jag2^tm2.2Grid	involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J	MGI:4829507

Genotype
MGI:4829507

hm1

• Allelic Composition: Jag2^tm2.2Grid/Jag2^tm2.2Grid
• Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Cleft palate, fused tongue, and syndactyly in Jag2^tm2.2Grid/Jag2^tm2.2Grid fetuses

mortality/aging

neonatal lethality, complete penetrance ( J:163652 )

• die within 1 day after birth

• phenotype is stated to be identical to that of Jag2^tm1Grid homozygotes

craniofacial

palatal shelf fusion with tongue or mandible ( J:163652 )

• palate-tongue fusions are present at E16.5; fusion of the tongue with the unelevated palatal shelves

cleft palate ( J:163652 )

• resulting from palate-tongue fusions

limbs/digits/tail

syndactyly ( J:163652 )

• syndactyly of both fore- and hindlimbs

digestive/alimentary system

palatal shelf fusion with tongue or mandible ( J:163652 )

• palate-tongue fusions are present at E16.5; fusion of the tongue with the unelevated palatal shelves

cleft palate ( J:163652 )

• resulting from palate-tongue fusions

growth/size/body

palatal shelf fusion with tongue or mandible ( J:163652 )

• palate-tongue fusions are present at E16.5; fusion of the tongue with the unelevated palatal shelves

cleft palate ( J:163652 )

• resulting from palate-tongue fusions