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Phenotype Image Detail
Image
Caption Phenotype of Jag2tm2.2Grid/Jag2tm2.2Grid mutant fetuses. (a-c) Cleft palate in Jag2tm2.2Grid/Jag2tm2.2Grid mutant mice. Coronal sections of E16.5 embryos show that the mutant has cleft palate and fused tongue. (c) Fusion of the tongue with the unelevated palatal shelves in the mutant mouse (black arrow). (d,e) Limb defects in mutant mice. A forefoot (left) and hindfoot (right) of E16.5 mouse are shown in each panel. Mutant embryos (e) exhibit syndactyly of both fore- and hindlimbs.
Copyright This image is from Xu J, Genesis 2010 Jun;48(6):390-3, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:163652
Associated
Alleles
Symbol Name
Jag2tm2.2Grid jagged 2; targeted mutation 2.2, Tom Gridley
Associated
Genotypes
Allelic Composition Genetic Background
Jag2tm2.2Grid/Jag2tm2.2Grid involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory