Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf3tm1(TCF3/HLF)Homy mutation
(0 available);
any
Tcf3 mutation
(39 available)
Tg(Emu-Zfp521)1Homy mutation
(1 available)
Tg(Mx1-cre)1Cgn mutation
(7 available)
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mortality/aging
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• within 6 months, pIpC-treated mice die of leukemia
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neoplasm
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• pIpC-treated mice develop acute B-lineage leukemia by 6 months of age unlike control mice
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Emu-Zfp521)1Homy mutation
(1 available)
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immune system
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• mice exhibit an increase in B cell precursors in the bone marrow compared with wild-type mice
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• mice exhibit an increase in B cell precursors in the bone marrow compared with wild-type mice
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neoplasm
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N |
• mice do not develop leukemia
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hematopoietic system
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N |
• mice exhibit normal hematological phenotypes in the peripheral blood
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• mice exhibit an increase in B cell precursors in the bone marrow compared with wild-type mice
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• mice exhibit an increase in B cell precursors in the bone marrow compared with wild-type mice
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Analysis Tools