Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox17tm2.1(icre)Heli mutation
(0 available);
any
Sox17 mutation
(28 available)
|
|
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normal phenotype
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• homozygotes are viable and fertile
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)1.1Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Sox17tm2.1(icre)Heli mutation
(0 available);
any
Sox17 mutation
(28 available)
|
|
|
cardiovascular system
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• heart size is similar to wild-type
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• in 26% of hearts at E17.5
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growth/size/body
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• body size is similar to wild-type
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Sox17tm2.1(icre)Heli mutation
(0 available);
any
Sox17 mutation
(28 available)
|
|
|
cardiovascular system
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• 5% of hearts show an atrial septal defect, statistically indistinguishable from wild-type
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• correlates to body size
|
growth/size/body