Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ehmt1tm1.1Tara targeted mutation 1.1, Alexander Tarakhovsky MGI:4418563 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E18.5 and P1
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• at E18.5 and P1
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• at E18.5 and P1
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• the specific neuronal cell architecture in the striatum and the hippocampus is not altered
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• almost completely lack a preference for sucrose
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• do not remember their negative experience
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• do not remember their negative experience
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• starting around 6-8 weeks of age in an open field make fewer total arm entries in an elevated plus maze
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• almost completely lack a preference for sucrose
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• make more entries into and spend more time in open arms in an elevated plus maze
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• slightly improved performance in some trials during standard accelerated rotarod analysis
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• in a new environment
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• in a new environment
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Kleefstra syndrome 1 | DOID:0060352 |
OMIM:610253 |
J:155739 | |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• travel significantly less than control mice in a new environment
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• reduction in vertical episodes in a new environment
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• travel significantly less than control mice in a new environment
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• reduced fatty-acid oxidation capacity in brown adipose tissue
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• temperature drop in cold-exposed mice
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• at fasted and glucose-stimulated states
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• temperature drop in cold-exposed mice
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• loss of induced increase in oxygen consumption after administering CL316,243
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• reduced fatty-acid oxidation capacity and fatty acid uptake in brown adipose tissue
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• without a change in food intake
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• higher amounts of lipids
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• reduced fatty-acid oxidation capacity in brown adipose tissue
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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