Ehmt2tm1.1Tara
Targeted Allele Detail
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Symbol: |
Ehmt2tm1.1Tara |
Name: |
euchromatic histone lysine N-methyltransferase 2; targeted mutation 1.1, Alexander Tarakhovsky |
MGI ID: |
MGI:4418499 |
Synonyms: |
G9af |
Gene: |
Ehmt2 Location: Chr17:35117445-35133028 bp, + strand Genetic Position: Chr17, 18.45 cM
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Alliance: |
Ehmt2tm1.1Tara page
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Germline Transmission: |
Earliest citation of germline transmission:
J:155931
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exons 23 and 24 were floxed and an FRT-flanked neo cassette inserted into intron 24 via homologous recombination. The selection cassette was then removed by flp mediated recombination. Cre-mediated recombination results in out-of-frame splicing and nonsense mediated decay of the mutant transcript.
(J:155931)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ehmt2 Mutation: |
55 strains or lines available
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Original: |
J:155931 Sampath SC, et al., Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Mol Cell. 2007 Aug 17;27(4):596-608 |
All: |
16 reference(s) |
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