Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
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mortality/aging
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• only 4% of pups survive to weaning
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cardiovascular system
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• at E17.5 in about 30% of mice
• however, no ventricular septal defect, arterial stenosis or obvious abnormalities of ventricular wall thickness are seen
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• in proportion to decrease in body size
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growth/size/body
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Sox17tm2.1(icre)Heli mutation
(0 available);
any
Sox17 mutation
(28 available)
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cardiovascular system
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• 5% of hearts show an atrial septal defect, statistically indistinguishable from wild-type
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• correlates to body size
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growth/size/body
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Tg(Nanog-cre)#Vlcg mutation
(0 available)
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cardiovascular system
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N |
• hearts lack atrial septal defects and are indistinguishable from wild-type
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
NipblGt(EUCE313f02)Hmgu mutation
(0 available);
any
Nipbl mutation
(124 available)
Tg(Tnnt2-cre)5Blh mutation
(1 available)
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cardiovascular system
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• only a single heart showed an atrial septal defect, statistically indistinguishable from wild-type
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• correlates to body size
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growth/size/body
Analysis Tools