Analysis Tools
neoplasm
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• mice show a decrease in incidence of metastases compared to double Trp53 and Nf1 heterozygotes, with 19.44% of mice with sarcomas showing metastases compared to 29.4% of double mutants
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• mice show a decrease in incidence of sarcomas compared to double Trp53 and Nf1 heterozygotes, with 13.89% of mice developing soft tissue sarcomas compared to 59.5% of double mutants
• less proliferation is seen in tumors
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immune system
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• 25% of mice exhibit splenic hyperplasia
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hematopoietic system
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• 25% of mice exhibit splenic hyperplasia
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growth/size/body
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• 25% of mice exhibit splenic hyperplasia
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