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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm3(CAG-luc)Tyj
targeted mutation 3, Tyler Jacks
MGI:3818723
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Krastm4Tyj/Kras+
Gt(ROSA)26Sortm3(CAG-luc)Tyj/Gt(ROSA)26Sor+ 		involves: 129S4/SvJae MGI:3818747


Genotype
MGI:3818747
cn1
Allelic
Composition		 Krastm4Tyj/Kras+
Gt(ROSA)26Sortm3(CAG-luc)Tyj/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(CAG-luc)Tyj mutation (2 available); any Gt(ROSA)26Sor mutation (1046 available)
Krastm4Tyj mutation (11 available); any Kras mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased lung tumor incidence ( J:141383 )
• following induction of expression using an adenoviral cre, mice develop lung tumors as in Krastm4Tyj

respiratory system
increased lung tumor incidence ( J:141383 )
• following induction of expression using an adenoviral cre, mice develop lung tumors as in Krastm4Tyj




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory