All Phenotypes Tg(Lck-Stat5b*)1Mafa MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Lck-Stat5b*)1Mafa
transgene insertion 1, Michael A Farrar
MGI:3776805

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tcf3^tm1Xhsu/Tcf3^tm1Xhsu Tg(Lck-Stat5b*)1Mafa/0	involves: 129X1/SvJ * C57BL/6 * FVB/N	MGI:3776807
tg2	Tg(Lck-Stat5b*)1Mafa/0	Not Specified	MGI:3776808

Allelic Composition	Tcf3^tm1Xhsu/Tcf3^tm1Xhsu Tg(Lck-Stat5b*)1Mafa/0
Genetic Background	involves: 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf3^tm1Xhsu mutation (0 available); any Tcf3 mutation (48 available)
Tg(Lck-Stat5b*)1Mafa mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased B cell proliferation ( J:132669 )

• B cell proliferation is increased

• however, unlike in mice expressing the transgene alone, B cell maturation in bone marrow and thymus is restored

hematopoietic system

increased B cell proliferation ( J:132669 )

• B cell proliferation is increased

• however, unlike in mice expressing the transgene alone, B cell maturation in bone marrow and thymus is restored

cellular

increased B cell proliferation ( J:132669 )

• B cell proliferation is increased

• however, unlike in mice expressing the transgene alone, B cell maturation in bone marrow and thymus is restored

Allelic Composition	Tg(Lck-Stat5b*)1Mafa/0
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased B cell proliferation ( J:132669 )

decreased mature B cell number ( J:132669 )

hematopoietic system

increased B cell proliferation ( J:132669 )

decreased mature B cell number ( J:132669 )

cellular

increased B cell proliferation ( J:132669 )

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