About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sh2d1atm2.1Vei
targeted mutation 2.1, Andre Veillette
MGI:3775432
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sh2d1atm2.1Vei/Sh2d1atm2.1Vei involves: C57BL/6 MGI:3775440


Genotype
MGI:3775440
hm1
Allelic
Composition		 Sh2d1atm2.1Vei/Sh2d1atm2.1Vei
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sh2d1atm2.1Vei mutation (0 available); any Sh2d1a mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased NK T cell number ( J:131618 )
• the number of NK T cells is decreased 90% compared to in wild-type mice
decreased IgE level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG1 level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG2a level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG2b level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG3 level ( J:131618 )
• following immunization with TNP-CGG
decreased IgM level ( J:131618 )
• following immunization with TNP-CGG

hematopoietic system
decreased NK T cell number ( J:131618 )
• the number of NK T cells is decreased 90% compared to in wild-type mice
decreased IgE level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG1 level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG2a level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG2b level ( J:131618 )
• following immunization with TNP-CGG
decreased IgG3 level ( J:131618 )
• following immunization with TNP-CGG
decreased IgM level ( J:131618 )
• following immunization with TNP-CGG




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory