Analysis Tools
normal phenotype
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• mice are fertile and indistinguishable from wild-type
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Allele Symbol Allele Name Allele ID |
Pax9tm1.1Hpt targeted mutation 1.1, Heiko Peters MGI:3723638 |
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| Summary |
5 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice are fertile and indistinguishable from wild-type
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• absent common carotid arteries in 9 of 9 mice
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• in 5 of 9 mice
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• in 1 of 9 mice
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| N |
• unlike in germline null mice, cleft palate is not seen
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• hypoplastic and absent from the normal position
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• hypoplastic and absent from the normal position
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• hypoplastic and absent from the normal position
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• hypoplastic and absent from the normal position
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• hypoplastic and absent from the normal position
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• hypoplastic and absent from the normal position
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• ossification center is shorter
• angle between the greater and lesser horns is reduced
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• reduced in length
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• extends laterally
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• significantly shorter
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• reduced to a stump
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• unlike in germline null mice, cleft palate is not seen
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• ossification center is shorter
• angle between the greater and lesser horns is reduced
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• reduced in length
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• extends laterally
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• cervical origin in 2 of 8 neonates
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• significantly shorter
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• reduced to a stump
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die at birth
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• mice are born with cleft secondary palate
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• mice are born with missing thymic lobes
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• mice are born with a hypoplastic tympanic ring
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• mice are born with preaxial digit duplication
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• mice are born with missing thymic lobes
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• mice are born with missing thymic lobes
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• mice are born with cleft secondary palate
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• mice are born with cleft secondary palate
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die at birth
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• tooth development is arrested at the bud stage
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• tooth development is arrested at the bud stage
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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• tooth development is arrested at the bud stage
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• the palatal processes of the maxilla is displaced laterally
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• the palatal processes of the palatine is displaced laterally
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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