Analysis Tools|
Allele Symbol Allele Name Allele ID |
Krt33a+ wild type MGI:3629954 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice with this mutation have a normal immune response to infection by Lysteria monocytogenes or by mouse cytomegalovirus (MCMV)
• peritoneal macrophages from mutant mice produce tumor necrosis factor alpha at levels similar to those of wild-type macrophages in response to stimulation by ligands for the seven toll-like receptors (TLRs) included in the TLR Signaling Screen: TLR1/2, TLR2/6, TLR3, TLR4, TLR7 and TLR9
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• the fur of mice heterozygous for this mutation appears unkempt, greasy, non-uniform and tufted or "spikey"
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• the fur of mice heterozygous for this mutation appears unkempt, greasy, non-uniform and tufted or "spikey"
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/24/2026 MGI 6.24 |
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