Krt33a^Plsh
Chemically induced Allele Detail

Summary

• Symbol: Krt33a^Plsh
• Name: keratin 33A; polished
• MGI ID: MGI:3800558
• Synonyms: Krt33a^m1Btlr
• Gene: Krt33a Location: Chr11:99902025-99907038 bp, - strand Genetic Position: Chr11, 63.35 cM, cytoband D
• Alliance: Krt33a^Plsh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, discovered by its visible phenotype among G1 progeny of an ENU-mutagenized male mouse, corresponds to a T-to-G transversion at nucleotide position 759 of the gene, in the fourth of seven total exons. This substitution results in replacement of tyrosine by aspartic acid at amino acid position 232 (Y323D), in the 2A alpha-helical rod subdomain of the keratin protein. (J:137498)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Krt33a Mutation: 30 strains or lines available

References

• Original: J:137498 Blasius AL, et al., Record for "Polished", updated 25th July, 2008. MGI Direct Data Submission. 2008
• All: 1 reference(s)