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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
H2-Kbm1
b haplotype mutation 1
MGI:3618114
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
H2-Kbm1/H2-Kbm1 B6.CBy-H2-Kbm1 MGI:5314231
cx2
H2-Kbm1/H2-Kbm1
Tg(TcraTcrb)1100Mjb/?
involves: C57BL/6 MGI:3783777


Genotype
MGI:5314231
hm1
Allelic
Composition
H2-Kbm1/H2-Kbm1
Genetic
Background
B6.CBy-H2-Kbm1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-Kbm1 mutation (10 available); any H2-K mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• marginally more urination and more feces in an open field test than in controls
• delayed acoustic startle response
• more slight head and body movements observed, especially for males
• more ultrasonic vocalizations recorded

vision/eye




Genotype
MGI:3783777
cx2
Allelic
Composition
H2-Kbm1/H2-Kbm1
Tg(TcraTcrb)1100Mjb/?
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2-Kbm1 mutation (10 available); any H2-K mutation (31 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• the transgenic TCR does not have a high affinity for the H2-Kbm1 allele leading to poor selection of T cell precursors for the CD8 single positive subset

hematopoietic system
• the transgenic TCR does not have a high affinity for the H2-Kbm1 allele leading to poor selection of T cell precursors for the CD8 single positive subset





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/24/2023
MGI 6.22
The Jackson Laboratory